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Trimethylglycine (TMG): Difference between revisions
→Heart Health and Homocysteine Levels
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=== Heart Health and Homocysteine Levels === | === Heart Health and Homocysteine Levels === | ||
* '''Homocysteine Reduction''': TMG acts as a methyl donor in the conversion of homocysteine, a non-proteinogenic α-amino acid, back to methionine. Elevated homocysteine levels are a known risk factor for cardiovascular diseases. By helping to lower these levels, TMG can potentially contribute to reduced risks of heart diseases. The US [[wikipedia:Food_and_Drug_Administration|Food and Drug Administration]] (FDA) approved betaine trimethylglycine (also known by the brand name Cystadane) for the treatment of [[wikipedia:Homocystinuria|homocystinuria]], a disease caused by abnormally high [[wikipedia:Homocysteine|homocysteine]] levels at birth. | * '''Homocysteine Reduction''': TMG acts as a methyl donor in the conversion of homocysteine, a non-proteinogenic α-amino acid, back to methionine. Elevated homocysteine levels are a known risk factor for cardiovascular diseases. By helping to lower these levels, TMG can potentially contribute to reduced risks of heart diseases. The US [[wikipedia:Food_and_Drug_Administration|Food and Drug Administration]] (FDA) approved betaine trimethylglycine (also known by the brand name Cystadane) for the treatment of [[wikipedia:Homocystinuria|homocystinuria]], a disease caused by abnormally high [[wikipedia:Homocysteine|homocysteine]] levels at birth. {{#pmid:15550695|pmid15550695}} | ||
* '''Endothelial Function''': Some studies suggest that TMG might improve endothelial function, thus potentially benefiting cardiovascular health. | * '''Endothelial Function''': Some studies suggest that TMG might improve endothelial function, thus potentially benefiting cardiovascular health. | ||