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Coenzyme Q10 (CoQ10): Difference between revisions
→Therapeutic Potential
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It also contributes to the regulation of mitochondrial function, such as influencing uncoupling proteins and the mitochondrial permeability transition pore, which are crucial for cell survival and apoptosis, respectively. Such regulation is particularly important as mitochondrial dysfunction is a noted characteristic of aging {{pmid|35199552}}. | It also contributes to the regulation of mitochondrial function, such as influencing uncoupling proteins and the mitochondrial permeability transition pore, which are crucial for cell survival and apoptosis, respectively. Such regulation is particularly important as mitochondrial dysfunction is a noted characteristic of aging {{pmid|35199552}}. | ||
=== | == Potential Therapeutic Role == | ||
Clinical and experimental studies indicate that CoQ<sub>10</sub> supplementation may exert beneficial effects on neurological diseases such as [[migraine]], [[Parkinson's disease]], [[Huntington's disease]], [[Alzheimer's disease]], [[amyotrophic lateral sclerosis]], [[Friedreich’s ataxia]], and [[multiple sclerosis]]. It is also of interest in the context of central mechanisms controlling blood pressure due to its effects on the brainstem rostral ventrolateral medulla and the hypothalamic paraventricular nucleus, which are related to [[cardiovascular hypertension]] {{pmid|35199552}} | |||
=== Neurological Diseases === | |||
Clinical and experimental studies indicate that CoQ<sub>10</sub> supplementation may exert beneficial effects on neurological diseases such as [[migraine]], [[Parkinson's disease]], [[Huntington's disease]], [[Alzheimer's disease]], [[amyotrophic lateral sclerosis]], [[Friedreich’s ataxia]], and [[multiple sclerosis]].{{pmid|35199552}} | |||
=== Hypertension === | |||
It is also of interest in the context of central mechanisms controlling blood pressure due to its effects on the brainstem rostral ventrolateral medulla and the hypothalamic paraventricular nucleus, which are related to [[cardiovascular hypertension]].{{pmid|35199552}} | |||
== Dietary Sources and Supplementation == | == Dietary Sources and Supplementation == | ||