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Coenzyme Q10 (CoQ10): Difference between revisions
→CoQ10 and Longevity
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CoQ<sub>10</sub> is integral to the electron transport chain on the inner membrane of mitochondria, facilitating the conversion of electrons from food into ATP. Its roles, however, extend beyond energy production. It is essential for uncoupling proteins and controls the permeability transition pore in mitochondria. Additionally, CoQ<sub>10</sub> is involved in extramitochondrial electron transport and affects membrane physicochemical properties. It impacts gene expression, which can alter overall metabolism. The primary alterations in energetic and antioxidant functions are believed to underpin its therapeutic effects {{pmid|35199552}}. | CoQ<sub>10</sub> is integral to the electron transport chain on the inner membrane of mitochondria, facilitating the conversion of electrons from food into ATP. Its roles, however, extend beyond energy production. It is essential for uncoupling proteins and controls the permeability transition pore in mitochondria. Additionally, CoQ<sub>10</sub> is involved in extramitochondrial electron transport and affects membrane physicochemical properties. It impacts gene expression, which can alter overall metabolism. The primary alterations in energetic and antioxidant functions are believed to underpin its therapeutic effects {{pmid|35199552}}. | ||
== | == Potential Longevity Benefits == | ||
=== Lifespan === | |||
=== Cellular and Molecular Roles === | === Cellular and Molecular Roles === | ||
As the only endogenous lipid antioxidant, CoQ<sub>10</sub> is critical in neutralizing free radicals, thus protecting against DNA damage and cellular dysfunction that are symptomatic of aging. By preserving cellular integrity, CoQ<sub>10</sub>'s antioxidant action is proposed to impede aging and potentially extend cellular lifespan. | As the only endogenous lipid antioxidant, CoQ<sub>10</sub> is critical in neutralizing free radicals, thus protecting against DNA damage and cellular dysfunction that are symptomatic of aging. By preserving cellular integrity, CoQ<sub>10</sub>'s antioxidant action is proposed to impede aging and potentially extend cellular lifespan. | ||