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Coenzyme Q10 (CoQ10): Difference between revisions
→Potential Therapeutic Role
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== Potential Therapeutic Role == | == Potential Therapeutic Role == | ||
CoQ10 has been widely researched for its potential in various health applications, including physical fitness, fertility, antiaging, diabetes management, and heart failure treatment. The therapeutic effects of CoQ10 are attributed to its enhancement of oxidative phosphorylation and its ability to mitigate oxidative stress. | |||
=== Neurological Diseases === | === Neurological Diseases === | ||
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=== Hypertension === | === Hypertension === | ||
It is also of interest in the context of central mechanisms controlling blood pressure due to its effects on the brainstem rostral ventrolateral medulla and the hypothalamic paraventricular nucleus, which are related to [[cardiovascular hypertension]].{{pmid|35199552}} | It is also of interest in the context of central mechanisms controlling blood pressure due to its effects on the brainstem rostral ventrolateral medulla and the hypothalamic paraventricular nucleus, which are related to [[cardiovascular hypertension]].{{pmid|35199552}} | ||
=== Diabetic Retinopathy === | |||
A particular area of interest is how CoQ<sub>10</sub> might help with a condition called diabetic retinopathy, which is a leading cause of blindness in adults. High blood sugar in diabetes can harm tiny blood vessels in the eye, leading to this condition. The damage causes stress to the eye and can lead to the growth of unhealthy blood vessels, worsening the problem [Citations 55-57]. Since CoQ<sub>10</sub> can help the mitochondria work better and has antioxidant properties, it might be useful in treating this eye condition. {{pmid|33641585}} | |||
Phase II clinical trials have been looking at CoQ<sub>10</sub> for an early diabetic retinopathy, also called non-proliferative diabetic retinopathy (NPDR). Patients who took 400 mg of CoQ<sub>10</sub> every day for 12 weeks to 6 months (different trials) showed improvements in blood flow and energy production in their cells compared to those who didn’t take it. These findings suggest that CoQ<sub>10</sub> could help slow down the worsening of this eye disease by improving blood supply and energy use in the eye, which could help prevent the eye damage from getting worse. More studies are needed to see if CoQ<sub>10</sub> can help stop diabetic retinopathy from progressing to more severe stages. {{pmid|33641585}} | |||
== Dietary Sources and Supplementation == | == Dietary Sources and Supplementation == | ||