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NADase: Difference between revisions
→Known NADase Enzymes
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|'''[[CD38]]'''||CD38 is a multifunctional enzyme involved in calcium signaling and plays a role in immune response, cellular metabolism, and NAD+ homeostasis.||Calcium signaling, cell adhesion, immune response.||Widely expressed in various tissues, including immune cells.||Involved in cellular aging processes, and its activity has been linked to a reduction in cellular NAD+ levels.||Chronic inflammatory conditions, some leukemias | |'''[[CD38]]'''||CD38 is a multifunctional enzyme involved in calcium signaling and plays a role in immune response, cellular metabolism, and NAD+ homeostasis.||Calcium signaling, cell adhesion, immune response.||Widely expressed in various tissues, including immune cells.||Involved in cellular aging processes, and its activity has been linked to a reduction in cellular NAD+ levels.||Chronic inflammatory conditions, some leukemias | ||
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|'''[[CD157]]'''||CD157, also known as bone marrow stromal antigen 1, is involved in monocyte and neutrophil infiltration during inflammatory responses and has implications in leukocyte trafficking.||Monocyte and neutrophil infiltration during inflammatory responses.||Primarily expressed in bone marrow and myeloid cells.||Its roles in inflammation might have implications in aging-related inflammatory conditions.||Autoimmune diseases, some cancers | |'''[[CD157]] / BST1'''||CD157, also known as bone marrow stromal antigen 1 (BST1), is involved in monocyte and neutrophil infiltration during inflammatory responses and has implications in leukocyte trafficking.||Monocyte and neutrophil infiltration during inflammatory responses.||Primarily expressed in bone marrow and myeloid cells.||Its roles in inflammation might have implications in aging-related inflammatory conditions.||Autoimmune diseases, some cancers | ||
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|'''[[SARM1]]'''||SARM1 (Sterile Alpha and TIR Motif Containing 1) is predominantly known for its role in programmed axon degeneration and has implications in neurodegenerative conditions.||Induces axonal degeneration after injury, involved in innate immune response.||Predominantly expressed in the nervous system.||Its role in axon degeneration has implications in aging-related neurodegenerative conditions.||Neurodegenerative diseases | |'''[[SARM1]]'''||SARM1 (Sterile Alpha and TIR Motif Containing 1) is predominantly known for its role in programmed axon degeneration and has implications in neurodegenerative conditions.||Induces axonal degeneration after injury, involved in innate immune response.||Predominantly expressed in the nervous system.||Its role in axon degeneration has implications in aging-related neurodegenerative conditions.||Neurodegenerative diseases | ||