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== Legal == | == Legal == | ||
CoQ<sub>10</sub> is not approved by the U.S. Food and Drug Administration (FDA) for the treatment of any medical condition.<ref name="NCI">{{cite web |last1= White |first1=J. |date= 14 May 2014 |title= PDQ® Coenzyme Q<sub>10</sub> |url= http://www.cancer.gov/cancertopics/pdq/cam/coenzymeQ10/HealthProfessional |publisher= [[National Cancer Institute]], [[National Institutes of Health]], [[United States Department of Health and Human Services|U.S. Dept. of Health and Human Services]] |access-date= 29 June 2014}}</ref><ref>{{Cite web |url=https://www.nice.org.uk/advice/es11/resources/mitochondrial-disorders-in-children-coenzyme-q10-pdf-1158110303173 |title=Mitochondrial disorders in children: Co-enzyme Q10 |date=28 March 2017 |publisher=National Institute for Health and Care Excellence |location=UK}}</ref> However, it is sold as a dietary supplement in the name of UbiQ 300 & UbiQ 100, not subject to the same regulations as medicinal drugs, and is an ingredient in some cosmetics.<ref>{{cite journal |last1=Hojerová |first1=J |title=[Coenzyme Q10--its importance, properties and use in nutrition and cosmetics]. |journal=Ceska a Slovenska Farmacie: Casopis Ceske Farmaceuticke Spolecnosti a Slovenske Farmaceuticke Spolecnosti |date=May 2000 |volume=49 |issue=3 |pages=119–23 |pmid=10953455}}</ref><ref>{{cite web |title=What is coenzyme Q10 (CoQ10) and why is it in skin care products? |url=https://www.webmd.com/beauty/qa/what-is-coenzyme-q10-coq10-and-why-is-it-in-skin-care-products |website=WebMD |language=en}}</ref> The manufacture of CoQ<sub>10</sub> is not regulated, and different batches and brands may vary significantly:<ref name="NCI" /> a 2004 laboratory analysis of CoQ<sub>10</sub> supplements on sale in the US found that some did not contain the quantity identified on the product label. Amounts ranged from "no detectable CoQ<sub>10</sub>", through 75% of stated dose, up to a 75% excess. | |||
=== United States (US) === | |||
CoQ<sub>10</sub> is not approved by the U.S. Food and Drug Administration (FDA) for the treatment of any medical condition.<ref name="NCI">{{cite web |last1= White |first1=J. |date= 14 May 2014 |title= PDQ® Coenzyme Q<sub>10</sub> |url= http://www.cancer.gov/cancertopics/pdq/cam/coenzymeQ10/HealthProfessional |publisher= [[National Cancer Institute]], [[National Institutes of Health]], [[United States Department of Health and Human Services|U.S. Dept. of Health and Human Services]] |access-date= 29 June 2014}}</ref><ref>{{Cite web |url=https://www.nice.org.uk/advice/es11/resources/mitochondrial-disorders-in-children-coenzyme-q10-pdf-1158110303173 |title=Mitochondrial disorders in children: Co-enzyme Q10 |date=28 March 2017 |publisher=National Institute for Health and Care Excellence |location=UK}}</ref> However, it is sold as a dietary supplement in the name of UbiQ 300 & UbiQ 100, not subject to the same regulations as medicinal drugs, and is an ingredient in some cosmetics.<ref>{{cite journal |last1=Hojerová |first1=J |title=[Coenzyme Q10--its importance, properties and use in nutrition and cosmetics]. |journal=Ceska a Slovenska Farmacie: Casopis Ceske Farmaceuticke Spolecnosti a Slovenske Farmaceuticke Spolecnosti |date=May 2000 |volume=49 |issue=3 |pages=119–23 |pmid=10953455}}</ref><ref>{{cite web |title=What is coenzyme Q10 (CoQ10) and why is it in skin care products? |url=https://www.webmd.com/beauty/qa/what-is-coenzyme-q10-coq10-and-why-is-it-in-skin-care-products |website=WebMD |language=en}}</ref> The manufacture of CoQ<sub>10</sub> is not regulated, and different batches and brands may vary significantly:<ref name="NCI" /> a 2004 laboratory analysis of CoQ<sub>10</sub> supplements on sale in the US found that some did not contain the quantity identified on the product label. Amounts ranged from "no detectable CoQ<sub>10</sub>", through 75% of stated dose, up to a 75% excess.<ref>{{cite web |url=https://www.consumerlab.com/news/coq10-coenzyme-q10-tests/01-13-2004/ |date= Jan 2004 |title= ConsumerLab.com finds discrepancies in strength of CoQ<sub>10</sub> supplements |website=ConsumerLab.com}}</ref> | |||
== Biochemical Function == | == Biochemical Function == | ||