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'''Genomic instability''' refers to the increased tendency of alterations in the genome during the life cycle of cells. It is a hallmark of aging and is characterized by a high frequency of mutations within the genome, including chromosomal rearrangements, DNA damage, and telomere shortening. This instability plays a significant role in the aging process and the development of various age-related diseases, particularly cancer. | '''Genomic instability''' refers to the increased tendency of alterations in the genome during the life cycle of cells. It is a hallmark of aging and is characterized by a high frequency of mutations within the genome, including chromosomal rearrangements, DNA damage, and telomere shortening. This instability plays a significant role in the aging process and the development of various age-related diseases, particularly cancer. | ||