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NAD+ Boosters: Difference between revisions
→Boosting NAD+ by Inhibiting NAD+ Consumers
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== Boosting NAD+ by Inhibiting NAD+ Consumers == | == Boosting NAD+ by Inhibiting NAD+ Consumers == | ||
NAD+ consumers are enzymes that use NAD+ as a substrate, reducing the available NAD+ in the cell. By inhibiting these consumers, more NAD+ remains available for other cellular processes. | NAD+ consumers are enzymes that use NAD+ as a substrate, reducing the available NAD+ in the cell. By inhibiting these consumers, more NAD+ remains available for other cellular processes. | ||
* '''[[Sirtuins]]:''' A family of proteins that deacetylate proteins and consume NAD+ in the process. Compounds like resveratrol can activate sirtuins, indirectly | * '''[[Sirtuins]]:''' A family of proteins that deacetylate proteins and consume NAD+ in the process. Compounds like resveratrol can activate sirtuins and the subsequent cellular effects can create an environment where cells might maintain or produce NAD+ more efficiently, which could indirectly support NAD+ availability. | ||
* '''PARPs (Poly(ADP-ribose) polymerases):''' Enzymes involved in DNA repair that also consume NAD+. Inhibiting PARP activity can help maintain NAD+ levels. | * '''PARPs (Poly(ADP-ribose) polymerases):''' Enzymes involved in DNA repair that also consume NAD+. Inhibiting PARP activity can help maintain NAD+ levels. | ||
* '''CD38:''' A glycoprotein that uses NAD+; reducing CD38 levels or activity can potentially elevate NAD+ levels. | * '''CD38:''' A glycoprotein that uses NAD+; reducing CD38 levels or activity can potentially elevate NAD+ levels. | ||