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{| class="wikitable" style="width:100%; text-align:center;" | {| class="wikitable" style="width:100%; text-align:center;" | ||
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! Formulation !! Enhancement in Bioavailability !! Solubility in Water | ! Formulation !! Enhancement in Bioavailability !! Solubility in Water !! Notes | ||
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| Standard Quercetin || 1 (baseline) || Very Low | | Standard Quercetin || 1 (baseline) || Very Low || Naturally occurring in various plants; serves as the baseline form of quercetin with poor solubility and bioavailability. | ||
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| Quercetin | | Quercetin Dihydrate || – || Moderate || Synthetic form with two water molecules associated; usually preferred for dietary supplements due to improved solubility. | ||
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| | | Quercetin Phytosomes || Up to 20 times || Low || Significantly increases oral bioavailability compared to standard quercetin. | ||
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| | | Nanoparticle Formulations || Several-fold increase || Variable, generally improved || Includes liposomal encapsulations; increased solubility and cellular uptake. | ||
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| | | Complexation with Cyclodextrins || Up to 10 times || Enhanced || Improves water solubility significantly, enhancing therapeutic effects. | ||
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| | | Co-administration with Piperine || Approximately 20% || Low || Inhibits metabolism of quercetin, improving its bioavailability. | ||
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| | |Liposomal Quercetin | ||
|Several-fold increase | |||
| | |||
|Liposomes enhance solubility and cellular uptake. | |||
|} | |} | ||