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Quercetin: Difference between revisions
→Pharmacological Properties
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*'''Molecular Weight:''' The molecular weight of quercetin is approximately 302.24 g/mol, a factor that influences its distribution and metabolism within the body. | *'''Molecular Weight:''' The molecular weight of quercetin is approximately 302.24 g/mol, a factor that influences its distribution and metabolism within the body. | ||
== | ==Formulations and Bioavailability== | ||
The pharmacological properties of '''Quercetin''' have sparked extensive research due to its potential therapeutic applications. Here we explore its absorption, metabolism, elimination, and mode of action within the body. | The pharmacological properties of '''Quercetin''' have sparked extensive research due to its potential therapeutic applications. Here we explore its absorption, metabolism, elimination, and mode of action within the body. | ||
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|- | |- | ||
! Formulation | ! Formulation | ||
!Alternative Names!! Relative Bioavailability | !Alternative Names!! Relative Bioavailability!! Notes | ||
|- | |- | ||
| Standard Quercetin | | Standard Quercetin | ||
| || 1 (baseline) | | || 1 (baseline) || Naturally occurring in various plants; serves as the baseline form of quercetin with poor solubility and bioavailability. | ||
|- | |- | ||
| Quercetin Dihydrate | | Quercetin Dihydrate | ||
| || – | | || – || Synthetic form with two water molecules associated; usually preferred for dietary supplements due to improved solubility. | ||
|- | |- | ||
| Quercetin Phytosomes | | Quercetin Phytosomes | ||
|Quercetin-Phospholipid | |Quercetin-Phospholipid | ||
| 10-20 | | 10-20 || Significantly increases oral bioavailability compared to standard quercetin. | ||
|- | |- | ||
| Nanoparticle Formulations | | Nanoparticle Formulations | ||
|Nanoquercetin, Quercetin Nanocapsules | |Nanoquercetin, Quercetin Nanocapsules | ||
| Several-fold increase | | Several-fold increase || Includes liposomal encapsulations; increased solubility and cellular uptake. | ||
|- | |- | ||
| Quercetin LipoMicel | | Quercetin LipoMicel | ||
| | | | ||
| 8-9 | | 8-9 || Encapsulating quercetin within a liquid micelle matrix | ||
|- | |- | ||
| Co-administration with Piperine | | Co-administration with Piperine | ||
|Bioavailability Enhanced Quercetin, Piperine-Quercetin Combination | |Bioavailability Enhanced Quercetin, Piperine-Quercetin Combination | ||
| Approximately 20% | | Approximately 20% || Inhibits metabolism of quercetin, improving its bioavailability. | ||
|} | |} | ||