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Spermidine: Difference between revisions

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==Dietary Sources==
==Dietary Sources==
Good dietary sources of spermidine are aged cheese, mushrooms, soy products, legumes, corn, and whole grains.<ref name="Ali20112">{{cite journal|doi=10.3402/fnr.v55i0.5572|title=Polyamines in foods: development of a food database|year=2011|last1=Ali|first1=Mohamed Atiya|last2=Poortvliet|first2=Eric|last3=Strömberg|first3=Roger|last4=Yngve|first4=Agneta|journal=Food Nutr Res.|volume=55|pages=5572|pmid=21249159|pmc=3022763}}</ref> Spermidine is plentiful in a [[wikipedia:Mediterranean_diet|Mediterranean diet]].<ref name="pmid29371440">{{cite journal|vauthors=Madeo F, Eisenberg T, Pietrocola F, Kroemer G|title=Spermidine in health and disease|journal=[[Science (journal)|Science]]|volume=359|issue=6374|pages=eaan2788|year=2018|doi=10.1126/science.aan2788|pmid=29371440|doi-access=free}}</ref> For comparison: The spermidine content in human seminal plasma varies between approx. 15 and 50 mg/L (mean 31 mg/L).<ref>{{citation|editor-surname1=Ciba-Geigy|periodical=Wissenschaftliche Tabellen Geigy|title=Sperma|edition=8|volume=Teilband Körperflüssigkeiten|publisher=CIBA-GEIGY Limited|location=Basel|at=pp.&nbsp;181-189|date=1977|language=de}}</ref>
Good dietary sources of spermidine are aged cheese, mushrooms, soy products, legumes, corn, and whole grains.<ref name="Ali20112">{{cite journal|doi=10.3402/fnr.v55i0.5572|title=Polyamines in foods: development of a food database|year=2011|last1=Ali|first1=Mohamed Atiya|last2=Poortvliet|first2=Eric|last3=Strömberg|first3=Roger|last4=Yngve|first4=Agneta|journal=Food Nutr Res.|volume=55|pages=5572|pmid=21249159|pmc=3022763}}</ref> Spermidine is plentiful in a [[wikipedia:Mediterranean_diet|Mediterranean diet]].<ref name="pmid29371440">{{cite journal|vauthors=Madeo F, Eisenberg T, Pietrocola F, Kroemer G|title=Spermidine in health and disease|journal=[[Science (journal)|Science]]|volume=359|issue=6374|pages=eaan2788|year=2018|doi=10.1126/science.aan2788|pmid=29371440|doi-access=free}}</ref>  
 
For comparison: The spermidine content in human seminal plasma varies between approx. 15 and 50 mg/L (mean 31 mg/L).<ref>{{citation|editor-surname1=Ciba-Geigy|periodical=Wissenschaftliche Tabellen Geigy|title=Sperma|edition=8|volume=Teilband Körperflüssigkeiten|publisher=CIBA-GEIGY Limited|location=Basel|at=pp.&nbsp;181-189|date=1977|language=de}}</ref>
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Note - spermidine content varies by source and age. See ref for details.
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==In grains, the [[wikipedia:Endosperm|endosperm]] contains most of the spermidine. One of the best known grain dietary sources is [[wikipedia:Wheat_germ|wheat germ]], containing as much as 243&nbsp;mg/kg.==
==In grains, the [[wikipedia:Endosperm|endosperm]] contains most of the spermidine. One of the best known grain dietary sources is [[wikipedia:Wheat_germ|wheat germ]], containing as much as 243&nbsp;mg/kg.==
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