Dose Conversion Between Animals and Human by Allometric Scaling: Difference between revisions

Dose Conversion Between Animals and Human by Allometric Scaling (view source)

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 == Human Equivalent Dose Calculation based on Body Surface Area ==
-Usually the correction factor (K<sub>m</sub>) is used to estimate the human equivalent does (HED) for different animal species. K<sub>m</sub> is estimated by dividing the average body weight (kg) of species to its body surface area (m²). For example, the average human body weight is 60 kg, and the body surface area is 1.62 m². Therefore, the K<sub>m</sub> factor for human is calculated by dividing 60 by 1.62, which is 37. As the K<sub>m</sub> factor for each species is constant, the K<sub>m</sub> ratio is used to simplify calculations.
+Usually the correction factor (K<sub>m</sub>) is used to estimate the human equivalent dose (HED) for different animal species. K<sub>m</sub> is estimated by dividing the average body weight (kg) of species to its body surface area (m²). For example, the average human body weight is 60 kg, and the body surface area is 1.62 m². Therefore, the K<sub>m</sub> factor for human is calculated by dividing 60 by 1.62, which is 37. As the K<sub>m</sub> factor for each species is constant, the K<sub>m</sub> ratio is used to simplify calculations.
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 |+Human equivalent dose calculation based on body surface area