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Hallmarks of Aging: Difference between revisions
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== Overview == | == Overview == | ||
[[File:Classification of Hallmarks of Aging.jpg|thumb|Scheme of the currently identified hallmarks of aging along with their classification.{{pmid|38095562}}]] | [[File:Classification of Hallmarks of Aging.jpg|thumb|Scheme of the currently identified hallmarks of aging along with their classification.{{pmid|38095562}}]]Aging is a complex process characterized by a gradual decline in physiological function. The hallmarks of aging are classified into three categories, each describing different aspects of the aging process: | ||
# '''Primary Hallmarks''': These are considered the main causes of cellular damage leading to aging. They are the initiating factors that, over time, drive the functional decline seen in aging cells and tissues. | |||
# '''Antagonistic Hallmarks''': These hallmarks are the response to the damage caused by the primary hallmarks. Initially, they may be compensatory or protective, but when chronic or excessive, they become deleterious, contributing to the aging process. | |||
# '''Integrative Hallmarks''': These hallmarks are the culprits of the phenotype of aging. They result from a combination of the primary and antagonistic hallmarks and are ultimately responsible for the functional decline in tissues and organs seen in aging. | |||
Below is a detailed table outlining each of these hallmarks, their descriptions, and the categories they belong to. | |||
=== The Nine Hallmarks of Aging (2013) === | === The Nine Hallmarks of Aging (2013) === | ||