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==== NAD+ Precursors ==== | ==== NAD+ Precursors ==== | ||
SIRT1 activity is closely linked to the cellular levels of [[NAD+]], a critical coenzyme involved in cellular metabolism and energy production. Increasing NAD+ levels through supplementation with its precursors, such as [[Nicotinamide Riboside (NR)|nicotinamide riboside (NR)]] and [[ | SIRT1 activity is closely linked to the cellular levels of [[NAD+]], a critical coenzyme involved in cellular metabolism and energy production. Increasing NAD+ levels through supplementation with its precursors, such as [[Nicotinamide Riboside (NR)|nicotinamide riboside (NR)]] and [[Nicotinamide Mononucleotide (NMN)|nicotinamide mononucleotide (NMN)]], has been shown to activate SIRT1, potentially mitigating age-related decline in cellular function and metabolism. | ||
==== Caloric Restriction ==== | ==== Caloric Restriction ==== |