Spermidine: Difference between revisions

Spermidine (view source)

84 bytes added , 20 October 2023

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 === Dosage ===
-The optimal dosage for human health and longevity outcomes remains unclear. In a separate study, 15 mg/d of spermidine was administered orally in 12 healthy volunteers for 5 days. Although spermidine was converted into spermine before entering the bloodstream, a significant increase in spermine levels was only observed at the 15 mg daily dose, indicating a threshold dosage for noticeable effects. Lower doses like 0.9-1.2 mg of spermidine per day didn't show changes in blood levels of spermidine, spermine or putrescine, suggesting that a certain amount of spermidine is necessary to see an effect<ref name=":0" />.
+The optimal dosage for human health and longevity outcomes remains unclear. In a separate study, 15 mg/day of spermidine was administered orally in 12 healthy volunteers for 5 days. Although spermidine was converted into spermine before entering the bloodstream, a significant increase in spermine levels was only observed at the 15 mg daily dose, indicating a threshold dosage for noticeable effects. Lower doses like 0.9-1.2 mg of spermidine per day didn't show changes in blood levels of spermidine, spermine or putrescine, suggesting that a certain amount of spermidine is necessary to see an effect<ref name=":0" />.
+On the supplemental market, in 2023 dosage between 1 and 6 mg/day were advertised.
 ==References==
 <references />
 [[Category:Orally Consumable Longevity Molecules]]